The Binding of Isaac: Rebirth

The Binding of Isaac: Rebirth

What character has the Best/Worst unlocks?
I generally don't see this topic brought up a whole lot, so let's discuss which character you feel has the best unlocks and the worst unlocks.

For the best unlocks, my personal pick is Apollyon. The Locust trinkets are all very useful to have (except for War, which ends up hurting me more often than not without bomb immunity), the Smelter is the only Hard mode unlock aside from Godhead that isn't useless (being able to gain the perks of your trinket permanently for the remainder of the run is great), and the Void has some great game-breaking potential.

For the worst unlocks, that honor definitely goes to Keeper. I haven't unlocked Keeper quite yet, but his unlocks are really stupid. And by unlocks, I mean the lack of any new items to use in future runs. Most of his "unlocks" mainly serve as bandages to make playing Keeper a bit easier for future runs. Plus, beating Hush, one of the hardest bosses in the game, as one of the most difficult characters in the game and all you get is that he starts with one extra coin? Just, why?
Last edited by Gallant T Derg; Jan 19, 2017 @ 4:26am
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Showing 1-15 of 16 comments
JellyPuff Jan 19, 2017 @ 4:55am 
The best unlocks are easy: The Lost. The Mind/Soul/Body a great, and the D100 and Godhead are instant wins. His unlocks manages to make the Angel Rooms at least somewhat desireable, but Soul/Mind/Body and Godhead can show up in Treasure Rooms as well and the D100 is exclusive to those.

The Keeper also unlocks Rib of Greed, Karma and Deep Pockets, which are good trinkets/items. Greeds Gullet and Crooked Penny are excellent (if they work).

It's still a close call between him and Cain. Evil Eye, Sack of Sacks and Silver Dollar are okay, but i have to go with Cain here, just for Abel clogging up the Golden Chest pool alone. His other unlocks are mostly useless as well, especially now, that Bomb/Coin bag can show up in Golden Chests since AB+. Sure, an early Bomb Bag is pretty neat, but wouldn't you rather have Steven or Guppy's Head instead?
Last edited by JellyPuff; Jan 19, 2017 @ 6:43pm
Mahasamatman Jan 19, 2017 @ 6:49am 
The best unlocks are from the Lost and the worst from Eve
Mahasamatman Jan 19, 2017 @ 6:49am 
Or Keeper
burn1none Jan 19, 2017 @ 7:00am 
Azazel deserves an honorable mention, some of his items are very good
pop pop Jan 19, 2017 @ 8:11am 
Originally posted by Jellypuff:
The best unlocks are easy: The Lost. The Mind/Soul/Body a great, and the D100 and Godhead are instant wins. His unlocks manages to make the Angel Rooms at least somewhat desireable, but Soul/Mind/Body and Godhead can show up in Treasure Rooms as well and the D100 is exclusive to those.

The Keeper also unlocks Rib of Greed, Karma and Deep Pockets, which are good trinkets/items. Greeds Gullet and Crooked Penny are excellent (if they work).

It's still a close call between him and Cain. Evil Eye, Sack of Sacks and Silver Dollar are okay, but i have to go with Cain here, just for Abel clogging up the Golden Chest pool alone. His other unlocks are mostly useless as well, especially now, that Bomb/Coin back can show up in Golden Chests since AB+. Sure, an early Bomb Bag is pretty neat, but wouldn't you rather have Steven or Guppy's Head instead?
About greeds gullet. On wiki you can read that you can get more coin hearts for keeper but he will die if you close the run and continue it
Violeta Jan 19, 2017 @ 9:15am 
For me the worst unlocks has always been cain,

The best unlocks are Lilith. Incubus/succubus are not only amazingly good, they can break so many challenges wide open its not even funny. Serpents kiss can save runs.

The lost's unlocks are pretty good too, but they can be so rare to find.
Last edited by Violeta; Jan 19, 2017 @ 9:15am
LSDBunny Jan 19, 2017 @ 10:26am 
Lost got great unlocks but I would dare to say Azazels are better. Because as great as The Soul or Godhead are, Azazel unlocks some of my favourite items, like The Satanic Bible and Abaddon. He also unlocks Lilith, who has some pretty cool unlocks as well.

Originally posted by Jellypuff:
The Mind/Soul/Body a great, and the D100 and Godhead are instant wins.

Godhead is neat but I really don't get why people say it's an instant win. The damaging aura never seemed as rewarding to me as a good damage boost.

Originally posted by Jellypuff:
Sack of Sacks and Silver Dollar are okay

Silver Dollar is more than ok. Since Mama Mega can open the entrance to blue womb, this trinket can make restock exploitation runs much easier.

Originally posted by 1981:
The best unlocks are from the Lost and the worst from Eve

No the worst unlocks are definitely Keepers. Especially considering how hard it is to unlock anything with him. And Eve has athame and sacrifial dagger as unlocks.


Violeta Jan 19, 2017 @ 10:29am 
Asthame is a pretty rubbish item.
Akaboogalo Boss Jan 19, 2017 @ 12:07pm 
They should change "Keeper now holds... A Penny!" to "Keeper holds greed's gullet" because of that new extra health mechanic.
LSDBunny Jan 19, 2017 @ 12:28pm 
Originally posted by Sashie:
Asthame is a pretty rubbish item.

At least combined with homing tears, it really isn't. You'll need to run into enemies on purpose tho and count on killing them with it, so you get the black hearts. Using it with the expectation to be a damage bonus in case you get hit, is the wrong approach. Also I haven't had a chance yet to try the dull razor on it, but I think it should activate it.
burn1none Jan 19, 2017 @ 12:36pm 
Originally posted by Sashie:
Asthame is a pretty rubbish item.
its kinda terrible unless you got goat head earlier but can be amazing with the right health combos especially with samson
Violeta Jan 19, 2017 @ 12:54pm 
Asthame is an item that shines if you have red hp and something like IV bag. Its in the devil deals which are about losing your red hp.

Keeping red hp stops polaroid invincibility. And rips really cool items like empty vessel. Plus maw of the void is a thing.
JellyPuff Jan 19, 2017 @ 6:46pm 
Originally posted by burn1none:
Originally posted by Sashie:
Asthame is a pretty rubbish item.
its kinda terrible unless you got goat head earlier but can be amazing with the right health combos especially with samson
Also, now we have Dull Razor. Assuming it works, it basically gives you a Maw of the Void every other room.
Last edited by JellyPuff; Jan 19, 2017 @ 7:00pm
LSDBunny Jan 19, 2017 @ 6:59pm 
Originally posted by Sashie:
Its in the devil deals which are about losing your red hp.

You don't need to get red heart damage for athame to activate. ANY damage to you and dull razor prolly (I dunno cause I didn't unlock that yet) will activate it. If there are enough weak enemies in the room, you can often get 2 black hearts out of it.
Violeta Jan 19, 2017 @ 7:07pm 
Originally posted by Affenkombat:
Originally posted by Sashie:
Its in the devil deals which are about losing your red hp.

You don't need to get red heart damage for athame to activate. ANY damage to you and dull razor prolly (I dunno cause I didn't unlock that yet) will activate it. If there are enough weak enemies in the room, you can often get 2 black hearts out of it.

A problem is starting at womb you take a full heart of damage. Black hearts destroy weak enemies when they blow up and asthame rewards black hearts.

I never said athame is useless item, just that its rubbish. It has many things working against it.
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Date Posted: Jan 19, 2017 @ 4:10am
Posts: 16