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http://bindingofisaacrebirth.gamepedia.com/Seeds#Special_Seeds
One can end the basement run after having gone through enough 'floors' by killing themselves (last life) on spikes in sacrifice room (soory fliers, u gotta find one of the other couple ways to glitch past). It doesn't seem to be a guarantee, but more often than not you should enter the final floor you have unlocked for that character and beating it will spawn the chest as normal. Still no achievements/advancement since its a seed. You can also use shovel instead of going in chest to keep going infinitely.