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Playing with 1 health is better anyway, because you can only have 12 hearts and red heart damage will reduce your devil deal chances. So you should always try to have many soul hearts and not as much heart containers. Also at 1 red heart you can enter the Boss Challenge rooms.
I didn't like dead cat at first either but as soon as I learned about what Guppy is and when to take it and when not to take it (taking it at too much health is at most times a bad idea), I realized that it can be a great item.
With tiny planet there some very very good synergies like brimstone but....it´s too opportunistic.
Cursed item is easyly a run killer for me - always.
Dead cat is also very ♥♥♥♥♥♥ to have because 9x 1 live is nothing against strong enemies.
Things i also don´t like are Mom´s bra.
Bob´s brain is very good i think because it can replace bombs if used correctly.
And every bomb item is always wellcome.
Tiny Planet, My Reflection, Soy Milk, Isaac's Heart, and possibly Fire Mind are all pretty bad.
and it's ZANY
...........A
...........N
...........Y
if anything you should be talking about mom's pad which fears enemies (fear isnt always good)
(it's also part of mom transformation)