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2muchNoskill
2easy
You're thinking of Remote Detonator.
Also screw the lost on greedier mode, it can't be done. I've tried around 200 times already i just can't beat greedier. They must have changed something.
Look out for tractor beam, that item plus some tears ups made my Lost/Greedier run. Also Godhead can spawn in the first item room, if you're lucky (made my Keeper run).
It really depends on the character.
@Vash try to get pyromaniac or host hat. Greedier can deal nearly no damage to you because 90% of his attacks are explosions. Or do it with chaos card if you are lucky to get it.
Hahaha, so much salt. Deals are not that good most of the time in Greedier on any character. You need to make the magic happen in the shop. Don't bother trying every run on Greedier, but stick with the ones with potential.
Also, if you're just looking for damage, you should get back to the drawing board.
But there are some exceptions to that. Somebody mentioned Remote Detonator : I would play the run even if I can't take it because of the 5 bombs advantage.
Will be a boring run from that point. Most other powerful items have at least fun synergies, Mom's Knife got none, except Brimstone+Homing and maybe Triple/Quad-Shot+Ludo. Loki's Horns can be fun too, but i play with KB/M, so going all lawnmower on the enemies just gets you carpal-tunnel'd.