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Not random at all, they require certain symptoms, usually a combination of symptoms (just like the projectile vomiting = coughing + vomiting, or oops = sneezing + diarrhea)
Runner = Enhanced Motor Control symptom and Engorged Quadriceps ability (in the horde part of the tree).
Tank = Bone Dysplasia and Anabolic Boost symptoms.
Spitter not 100% sure but its one of the range attack symptoms + vision symptoms.
There is no such symptom as Enhanced Sensory Control.
Combos can be found here.
http://steamcommunity.com/sharedfiles/filedetails/?id=233828665