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Anyway, devolving a free mutation is wrong 99% of the times. So you don't need ionized helix.
Don't believe the noobs who tell you to take no symptoms all the game, and to devolve every mutations instantly. They should learn how to play before talking.
Virus mutates constantly, so it punishes you for devolving and not just going with its own personal flow, it starts with like a 6 point devolve cost which means ionised helix will probably make it 4 or so. (Besides, virus is more fun by letting it evolve, and buying all 3 mutation abilities plus the animal transmissions, AND bringing in the darwinist gene for even more mutating. Try surviving when I have ALL the symptoms for free world!)
Meanwhile nice, simple bacteria has a 1 or 2 cost, so helix actually makes the cost go negative (which means you get paid).
Regardless though, every devolve increases the cost by 1. So if you devolve crazily, even bacteria will cost a fortune.
The 'stasis' genes are far better in the long run, cause you may need 1 or 2 devolves a game, you WILL need a dozen or so symptoms and the cost to buy a symptom increases every time you buy one without sympto stasis. Or buying 12 spore bursts on fungus goes a lot faster with patho stasis.
You can also mitigate mutations some by grabbing base oxidation or base hydrolysis which allow transmissions or abilities to evolve sometimes, which are almost always good to get.
Interesting take. I've found on more than one occasion that holding off on Symptoms until almost everyone is infected, and saving Evolve-Points with Ionized Helix is one of the easiest ways to clear the Bacterial level.
scientist will always discover your plague so using no symptoms cannot be done here.