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Ember has poor endgame damage scaling so I can't recommend her.
The best frame's to do damage Endgame is valkyr/nidus. Nidus is a tank and does massive damage . Press 2 at a group of enemies and do puncture/corrosive damage and spam 1.
Valkyr just kill's everything in melee range, If your low on health press 4 then you get it back.
Banshee... i cant understand people not using her much yes she's squish but sonar increases your damage and your parties damage by such MASSIVE amounts... its ridiculous... Sonar is the BEST damage buff you will get in game i cant think of a better raw damage buff...
Here is a chart that shows the effective HP of a Grineer Ballista from level 1 to 200.
http://i.imgur.com/IxR7qaJ.png
The enemy has 6386hp but 97,23% reduction via armor, giving it an effecktive HP of about 230000
Frames that can strip armour, or squads using 4x of the Corrosive Projection aura, are therefore pretty much a requirement.
Armour stripping is even useful against the Corpus, some of their more dangerous units can have a fair bit of armour.
Frost and Saryn are the frames that come to mind that can strip large amounts of armour in a large area. There are others that can do it in a smaller area, or single targets, like Banshee or Ash with augments.
For directly dealing damage, probably Excal or Mesa, but I'm unsure.
Low lvl AoE: ember
Low lvl AoE defence: saryn with 4 corrosive or banshee
High lvl AoE: mesa, limbo(?)
High lvl AoE defence: banshee or mesa(for very high before 150 (if Power is 130% like is mine))
High lvl single targets (run and shoot): mesa, excal(?), valk, banshee.
I dont have Nidus but i'm sure that he is good in terms of AoE and survivability
C urrently Limbo out plays Mesa. Till cataclysm gets nerfed.