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Sort of his signature.
Someone need to brush up on thier alchemy lessons. Nightshade is a poisonous plant with the following 3 negative effects. Damage health, burden, and damage luck. As a light weight ingredient its often used a base for poison up until journeyman level, then it tends to become a ingredient used when you have a lot of other effects, and just need a liiteweight ingredient to throw on the health damage.
The main reason you use it less after journeyman level (in case of assassin) is due to its positive effect of fortify magicka. After journeyman level there are simply to many other ingredients with this effect, thus causing lots of conflict.
Lorewise it is often used in assassin based rituals. It is used both in Dark Brotherhood rituals, as well as Moran Tong rituals involving worship of Mephala. (who I can;t remember, may use another name as well , but it boils down to it beign Mephala the webspinner.)
It all stems and bases from Mephala to a degree. The webspinner is a patron of assasins and spies. Spies and forgers, help weave the strands of the web, assasins severe them.
It never made since to me that bodies will just stay on the road for around three in game days, especially with the Imperial Legion riding by all the time.
But then again, it never made sense to me to wear full plate mail all the time either. Having been in the SCA, I know that stuff get murderously hot in the full sun. That's what breast plate is for.
No kidding, as someone who owns chainmail, I just have to say "NO WAY that ♥♥♥♥ is light armor!"
Chainmail can be nearly as heavy as later date plate armors (as metaluurgy gets better they learned how to lighten it yet still keep it durable), and is the reason why some game have a medium armor category.