How would you build Eisenhorn?

[DaniVegaz]

I loved listening to the audiobooks back in the day.
"playing" as him or embodying him would be awesome, but im not sure how i would go around doing that. any tips?

[UnCivilServant]

They don't have enough plot armor in the game to cover playing Heretic that hard.

[kotor_fan]

I'd say it would be something that can't be done (I think, but not sure)
Operative Psyker (think Idira, mental powers) into Vanguard

Eisenhorn is mediocre psyker with strong resistances at the start of books, but highly skilled melee combatant. By book 3 and onwards, he's psychic powerhouse while still being great melee combatant.

If anything, inquisitor companion is very close to it, just different psyker class than what Eisenhorn would be.

Definitely starting dogmaric with some iconoclast mixed in, and just tiny pinch of heretical here and there. Later...well that would be spoilers for the books :P
Minor edit since it's there already: For later, I definitely agree with uncivil servant.