(Found Solution) Fatal Error Address: 0x0 (filename not found)

[Abbat Unkaam]

I've played about a hundred hours of Dishonored my old gtx 480 and recently got a rx 580.

Since then every time I have tried to run Dishonored this error displays.

I've tried re-downloading my rx 580 drivers, running windows in safe mode, reinstalling and changing the bDisablePhysXHardwareSupport= line in DishonoredEngine to False.

I haven't tried DEP because I can't get it to work.

If you have any solutions plz help.

[Abbat Unkaam]

If nothing is working go to C:\Program Files (x86)\NVIDIA Corporation\PhysX\Engine\DB8A731FDBD5 or what drive windows is downloaded on and delete
PhysXCore.dll you will probably have to reinstall the game after that. This issue was really frustrating, I'm happy I found an solution.

[Dukátek]

This solved the problem for me, thanks!