Pistol/Blood

[VonBaronson]

Solo Content (Scenario, Questing):

Active
Flourish - Replenish energy when you need it
Eldritch Scourge - Great damage plus debilitated
Clean Slate - Emergency heal
Hair Trigger- Forced to have a basic, ugh
Controlled Shooting - AOE
Unload - Main ability for any single targets

Passive
High Roller
Win Streak
Jackpot
Double Down
Desolate

Group Content (Dungeon, Lair):

Active
Runic Hex
Eldritch Scourge
Desecrate
Reap
Seeking Bullet - You should never need aoe, but it's helpful for some areas like polaris
Unload

Passive
Fixed Game
Desolate
Paroxysm
Contaminate
Double Down

Your boss damage rotation goes:
Runic Hex - Eldritch Scourge - Desecrate - Reap - Unload until Runic Hex is back up

Weapons:
Pistol - Soviet CB-3 Annihilators of Havoc/Destruction/Energy
Blood - Eldritch Tome of Havoc/Destruction/Alacrity

Talismans:
None of these are required, just my opinion on the best. Make sure that any talisman you use are attack rating and you will be fine.
Ashes of Crushed Cities
Skadi's Ring
Seed of Aggression
Iron-Sulfur Bracelet
Cold Silver Dice
Barbelith Wire
Sigil of Ambition

Gadget:
Mnemonic Guardian - Werewolf
Best for your dps, but some fights or groups may require you to slot a utility gadget for specific situations and that's fine.

Glyphs:
When at legendary accurate glyph
1x Accurate
6x Fierce
2x Devastating
Until you have 2x lvl 20 mythic accurate glyphs to combine do this
2x Accurate
5x Fierce
2x Devastating

Signets:
Head - Rituals
Finger - Gambler
Neck - Outlaw
Wrist - None
Luck - Laceration
Waist - Matter Creation (Time and Space if you mainly use utility gadgets)
Occult - Any of them are fine

Always looking to improve my builds. Thank you for reading.