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For boarding cloning bay makes it less riskier. You don't even have to care to beam them back to your ship if low on health. For the classic medbay final fight medbay is naturally better. However, if s*** hits the fan and you have cloning bay, just open every single door... And speaking of doors: you can "exploit" cloning bay by killing badly damaged crewmembers so that they get their health back. My opinion is that upgrading cloning bay just to get better passive healing rate is not justified.
Cloning bay is a little bit better, but not better enough that I buy a cloning bay if I started with medbay. It's not better enough that I don't buy medbay with a Slug B if I find that first...
That said I have not tried the healing teleport augment coupled with clone bay, which on paper sounds excellent.
Maybe I'm too stuck in my ways, but I find the ability to control healing to outweigh the benefits cloning brings.
Honestly, I don't see the appeal of the cloning bay, except for some gimmicky playstyles like zoltan bombing. Medbay allows for more in-depth, micromanagement focused strategies, normally with much better results.
IMO it's ALWAYS worth the 40 scrap and augmentation slot.
Mind you I play almost exclusively on Easy difficulty so the odds of those random occurances happening only increase the harder you make it. This is the reason I think the DNA Bank is always worth it.