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If you're not into getting it the natural way - pick any wave, kill everything except one enemy and do the above. Try it with wave 1 of any map without towers, so you don't accidentally kill off the last lume. Big maps are probably easier (Cluster, Abandoned Lab).
Maximizing safety - Rex+Battle Rifle, Skye with Slowing Presence or Sweet with Rymskdor/Slowing Presence. This gives you double+rocket jump to eject, if you're not comfortable with jump-ejecting (jump up and get hit = get thrown waaay back, but you'll have to count hits to get to 1 HP simultaneously).
Hydra Blood might bug out and give you near-instant regen, so if you're specifically achiement-hunting I'd avoid that one (although it's not that regular).
But if you only want this achievement (because let's be honest, this achievement sounds pretty cool) then I have to say that DoomyDoom summed it up very nicely.