The absolute strongest possible combo, impossible to beat.

[Melissanoma]

Requires two specific cubes and one of either of two specific perks.

PATCHUP:
3 mana. After this is created heal the cube below by 2hp
FreePlacement

AND

GRAB:
5 mana. After this is created exile the cube below and add a copy into your hand, if its not an ally also lose 45 mana

---

THE CRAFTY
gold perk
At the start of each battle all other cubes in your hand gail all abilities and half the manacost of the cube in the 3rd slot of your hand

OR

FUSIONING
random encounter perk
At the start of each battle add a combination of the cubes in the first two slots of your hand to your hand with infinite uses

---

Together they give you a cube that says:

6 or 8 mana (depending on the perk)
exile a normal leader.

57 or 61 mana
exile a boss leader surrounded by shields

If you start battles paused, then you just place it, unpause, and win with 00.00.01 on the clock. Any difficulty, any debt. Even works on The Dream post-game challenge that makes enemies unkillable.

Well, that or you can use it on your own leader and instantly lose. GRAB should probably be changed to not work on leaders.

[ollj]

because [time-pipe] connects to bullets, that are created by [bullet-recycling], but such a bullet moves out of time-pipe-range, removing the [time-pipe], creating another bullet, reconnecting a time-pipe... you get 1 bullet per FRAME from a thorn-hedge (for each Time-PipeEnding+height) , that initiates this loop by spawning the hedge above it. a thirn hedge does 2 damage per frame on the whole line. and this is quickly done over 3 lines.

https://i.imgur.com/AdpSuC4.jpeg

[Melissanoma]

I dunno, making a bullet every tick sounds pretty cool (and to be honest I'd love to get that build), but it's more than six seconds in and you haven't won yet?

https://i.imgur.com/bsJIjt4.jpeg

[JackThejil]

Had a really cracked one recently that not only was ending the match in 1 tick, it was ending the match with my main leader up ~2 billion health on tick 0, and all the (three, from curses) enemy leaders both about the same down and poisoned (poisoner's vial) for that amount yet again (on top of hundreds of burns, slow downs, etc.; rainbow is a hell of a drug). All with zero input from me. Upgraded safety procedures gets incredibly, wildly broken.

Ultimately had to stop the run because starting a match gummed up the game so bad the only key input it reacted to was alt-f4, heh. That's how you know you're winning, when the game just gives up :V

[Draco18s]

Cloud Hammer + Infester (class) + Flames of Aggression + Unstable Egg (Swarm) + Veteran/Rusted Plate/Or other "take damage on spawn" effect.

https://cdn.discordapp.com/attachments/707234204248965223/1200712139418112010/image.png

https://www.youtube.com/watch?v=Ruz0J4XOVq0

[JackThejil]

Oh, pyro with bee hives and some humming chain reaction is a lark; Fairly unworkable due to lag, but it turns half the map into unending bees. Anything added on that'll get stuff to spawn on the right side of the map and it stops being just half the map.

Had a fun one that was that plus an upgraded flames of aggression; basically turned half the map into bees and the other half into fire. Most fun on mine maps, though -- those ended up looking like this: https://i.ibb.co/94NVdwQ/the-air-is-now-bees.png

[test]

I took the allies create bullets on death and flying allies create falling projectiles and it filled my map with bullets, since I was playing with infestation character that also filled the whole floor with my monsters, was very strong

[Abstruse Paradox]

In prior versions, you could simply banish the enemy leaders from the game. I'd consider this superior by means of less effort spent each battle.

[NexionSE of the Cm.G.]

had the random from hand trait perk + bullet spawn from ally in air and the knight army cube basicly flooded the map with bullets and knights, added the 3rd hand trait perk and put a do dmg to 3 random target + freeze from cryo and got insta win at 10000+ dept.