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body shredder is possibly the mostly insanely OP card for the first 4 dungeons, gem it with 2x innate runes and it does 3x bleed damage when played. Tool the rest of your deck toward bleed damage and thats like 200 damage.
You can even get it to 25% surplus for a good chance at double tapping before you need to burn a turn resting.
Just use fireball/heart piercer/bloodsucking with a postorioi rune so you can get the auras at max stacks before the boss.
then use pick up stone/treasure bag gemmed with 40% surplus to play a ton of cards to maximize your burn/bleed/lifesteal auras (gem treasure bag with an innate rune for 2 items instead of 1).
The 3 basic cards with no mods and 5 gem slots can become 6 bleed/40% surplus cards and that helps a ton in quickly building up a bleed stack to exploit with body shredder.
Include the card that gives the combo aura when discarded too that way you can build up a nice combo stack while spamming your cheap surplus cards and make treasure bags bandages heal for like 10+ instead of 2.
Thanks so much! When you say postorioi rune, do you mean Charge Up Rune? Also do you happen to know which card it is that gives the combo aura when discarded? Not sure if I'm overlooking anything.
The posteriori? gem is the one that increases the star level of the discard skill a card has. (so if you gem fireball with 1 you get 2 stacks of burn per attack rather than 1).
Im unsure if that gem unlocks already or if its unlocked at the end of this dungeon though, but its obviously one of the best in the game since you can gem 4 of them into a card discard it once get a max aura stack then regem it mid dungeon to remove the massive mana cost.