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Impossible mode is only to unlock the handcannon and suit.
If you go NG+ on impossible you simply just lose all your items from your last completed save and you are playing Impossible mode again with no NG+ enemies.
Game even warns you that impossible mode is a one time playthough mode. You cannot play NG+ on that difficulty if you complete it.
Just sell the medium and big healling items and buy nodes. Your plasma cutter will kill anything if upgraded and you won't need other guns.
You can play Impossible NG+ using a completed Impossible game save.
Well then, here's a video proof that you can play Impossible on NG+, enjoy!
https://youtu.be/Y4O6HbmN9KQ
However you did not show me further that you actually have your gear, so that proves almost nothing but your words !