Best Usage Of Zybe?

[Brannagan]

I'm only a few hours in, most Zybe I can get is 3 before I get stuck in a stalemate and need to prestige so wondering what best way to spend them are? I've done time-shift which is good. Fire breath which combos nicely with fire arrows especially with the supershatter perk and I always try to save for a garden too so I only really have 2 Zybes to play with

[Lackadaisy]

It's situational depending on where you've allocated your talent points. Try to look at what costs Zybe and how that impacts where you've put your talent points to maximize the synergy.
For example, the talent Bullet Breath combos with the zybe building upgrade Fire Breath.