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There's an event to corrupt cards, but I don't think there's one for items.
In adventure mode corrupted Items have a 3% chance and +0.3% per each madness level
A tip I've been using is to set M1 with Impending Doom which the game reads as M2. This makes the game a bit more challenging but not to the point of stressing you out and has an increased chance of drops.
Depends on the game but the last one I had there were a fair amount