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Took out all but 6 of the gods in one go, three of them took a second key. Then it was coming up with different parties for the remaining 3
I've just tried it and it didn't work =( two of her monsters survived and killed all of mine =(...it was my last key
Did you spam Affliction even after your enemies were thoroughly covered in debuffs? -Also, try adding minions to the mix. I deal in a lot of indirect damage with my current team. Relics are worth it, since their abilities also get spammed with a Doombringer.
Finally, check the realm you're facing off against Nether bosses. Some offer more bonuses with attack-useful buffs and debuffs, or defense, etc.
You're right; I missed binder_diego's mention of a "last key," since the OP didn't mention it. Rest of the comments about using Doombringer to bring doom to Muse still work.
I would have sworn I encountered Muse as a Nether boss, but I could have misremembered after some long playing sessions. Muse is not listed under Nether Bosses in the Codex.
Still a winnable fight at the Gate using Doombringer, tweaked to spam Affliction, etc.
I'm only at depth 314 right now, a handful of relics between lvl 20 and 40. Do I need to wait and unlock more? Thanks in advance.
Any suggestions for defeating Muse specifically with Tribalist?
Also Spell Lock spell gem!
I guess you already know this, but since you most likely have a mono-class build, you benefit greatly from the Chaos Nexus spell.