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control panel
system
advanced system settings
performance "settings"
data execution prevention
"turn on DEP for all programs and services except those i select"
add gtasa.exe
control panel
user accounts
"change user account control settings"
turn slider down to "never notify"
Run the game as administrator if you didn't already do that, check "disable visual themes", "disable desktop composition" & "disable display scaling on high dpi settings". Try Windows XP SP3 or Windows 98/Me. Update your display and sound drivers. Check for Windows updates including optional/hidden updates. Close any background programs before playing including antivirus. Also verify the game cache incase it's a bad install or even reinstall the game. Disable Steam Community ingame. Some older games crash or act strange if this is on.
You could also try minimizing the game at the menu screen, open task manager, right click gtasa.exe, click "set affinity" and uncheck all CPU cores except 0 leaving only 1 CPU core to run the game. This fixes issues with some older games that were made for one core and act strange on multi-core CPUs.
Some people fixed issues with this game by deleting their gta_sa.set file from the SanAndreas User Files folder. I don't think that will help your situation tho.
I'm out of ideas. I've gotten this game to run on different PCs easily. I'm not sure why you're having such bad luck.