If your patron goddess is Iomedae, do you get more interactions in the game overall?

[A]

I'm at Wintersun and I got a prompt from Erastil via stag as flavor text with his saying "never trust fools" or something like that. Now, I wonder, does Iomedae give more things like this considering she keeps being mentioned a lot?

I did not check, but if Baphomet is an option, are there interactions with his cultists and such?

[Schlumpsha]

All playable deities have varying degrees of interaction, including Iomedae. The same holds true for the Green Faith and Atheism as well.

Baphomet isn't available as an deity. But you can pledge yourself to him as an Demon.

[Cutlass Jack]

I think there's at least some interactions for every diety choice (even athiest!)

For example if you worship Cayden (god of drinking) you can invoke him to get a buff defending the inn in the first Act.

If you worship Callistia you get to invoke her name on vengeance topics and get buffs from her.

I'm sure Iomedae has hers too.

[Super Cosmic Space Magnet]

My favourite interaction is if you have Desna as your patron but then kill the Desnan priests in Act 1. You get a HORRENDOUS debuff as the game smacks you on the wrists. It really wants you to reload a save and take the Azata route, as there's also entire new dialogues for Arue's romance if you're a Desnan.

Other ones include: Gorrum making you super-sayan during the fight in Act 3 against the Kelid, Sarenae giving you a massive buff to fire damage when you go to Wintersun, and Callistra buffing you when you fight Minagho (if you swore revenge on her in Act 1).

Also when you enter the Abyss you get a unique line of introspective dialogue where your character reflects on how it feels to be there, based on your god. If you worship Gozreh your character will be profoundly unhappy and never felt further from home, whereras a Callistra worshipper will be disgusted but excited at the opportunities for unfettered revenge. Every deity seems to have their own interaction here, which I truly adore.

Generally the deities do have minor reactivity and little lines of dialogue throughout the story, but nothing that will radically reshape the plot. Usually it's just some flavour text or giving you a buff for one fight.

[A]

Originally posted by Super Cosmic Space Magnet:

My favourite interaction is if you have Desna as your patron but then kill the Desnan priests in Act 1. You get a HORRENDOUS debuff as the game smacks you on the wrists. It really wants you to reload a save and take the Azata route, as there's also entire new dialogues for Arue's romance if you're a Desnan.

Other ones include: Gorrum making you super-sayan during the fight in Act 3 against the Kelid, Sarenae giving you a massive buff to fire damage when you go to Wintersun, and Callistra buffing you when you fight Minagho (if you swore revenge on her in Act 1).

Also when you enter the Abyss you get a unique line of introspective dialogue where your character reflects on how it feels to be there, based on your god. If you worship Gozreh your character will be profoundly unhappy and never felt further from home, whereras a Callistra worshipper will be disgusted but excited at the opportunities for unfettered revenge. Every deity seems to have their own interaction here, which I truly adore.

Generally the deities do have minor reactivity and little lines of dialogue throughout the story, but nothing that will radically reshape the plot. Usually it's just some flavour text or giving you a buff for one fight.

Is the arue romance better overall if you're going azata? I was planning to romance her on my second playthrough but i was thinking of Aeon for that route.

[Super Cosmic Space Magnet]

I think so, yes. She has quite a lot of unique dialogue for the Azata route so you'll see more of her flavour by going through it. There is also some pretty amazing dialogue if you go for the Demon route but are still kind and nice at every opportunity.

Aeon is sort of the complete antithesis of Arue - I think it might even be impossible to keep her in your party if you pursue it. They are the embodiment of cosmic order and everything residing in and behaving according to the rules of its plane, so a demon trying to ascend from the abyss is completely unacceptable to them. To an Aeon, Arue SHOULD be a murderous succubus monster.

[Cutlass Jack]

She does like it if you go Azata, but that only seemed to affect dialogue outside of the romance stuff from what I noticed.

[Morphic]

Originally posted by Super Cosmic Space Magnet:

To an Aeon, Arue SHOULD be a murderous succubus monster.

Unless you are a Renegade Aeon, since they are more emotionally driven/bend the rules. Though you'd miss out on Aeon's special/specific ending and unique story elements since you have to be a True Aeon for that.

By the by, I've done a True Aeon playthrough and romanced Arue just fine. You'll just have to pick Neutral options from time to time instead of always Lawful. Personally, I chose various options ranging from Chaotic to Evil to Good and Lawful. Overall kept myself in Lawful Neutral throughout and True Aeon. I RP'ed it as you are initially not a full Aeon and thus are able to make some mistakes, then later on selecting certain options for "cosmic balance". (Like saving Aasimars/Slaves from the Abyss since they technically shouldn't be there to begin with, or going full rage murderhobo since you're in the Abyss and that's what Abyssians do)

[Nero]

I really liked this stuff. But it's not that much in the game (tbh why should the devs waste hours of creating if only like 0,1% choose eg Lamashtu)

Nethys has a nice dialog where your characters asks Areelu at the end of act 2 something like "Nethys destroys with one hand and creates with the other. What do you create?" And she simply nods as an answer.

[Raven]

I am currently playing Iomede paladin, cus why not? but from previous plays, some of the most funniest interactions/extra deity dialogue I got came from playing an elf with the one goddess of vengeance that elves really like to worship. You get to say some really spiteful/vengeance stuff and there isn't consequences that seem to crop up like they usually do (like an alignment shift and stuff). Some are just hilarious, a few are kinda dark.

So far as Iomede goes, I got an extra interaction with Radiance, but not sure if that's because of Iomede or because I'm a paladin (I'm leaning that its the latter)

[Immortal Reaver]

Lich has a lot of interactions with both Urgathoa and Pharasma.
I started playing as Rovagug worshipper, but it seems to have quite nice interactions too with Demon Mythic Path choices so far.