How do i know when to start using the next augments?

[Murphy's Lawyer]

like im rebirthing to boss 140ish, i did all the aug challenges. I can level scissors combo to like 10,000 while i sleep over night.

should i be using a higher augment?

a lot of stuff online says scissors is best for a 'long" time. but when is it time to move on? I searched and don't really see anyone answering. something about 3801? does that mean i should move on if i can scissor up to 3801? cuz i can easily. when do i move on for milk? or do i have it wrong.

someone needs should make a guide that actually has hard cut info of when to start min/maxing what, a lot of guides are just kinda gibberish general stuff without an actually "do this at this level"

[Ibn Battuta]

Personally, I'd just give it a go for one rebirth.

What's the worst that can happen?
Well, approximately, you have a bad rebirth and kill fewer bosses. Since it didn't work, you change back and it takes 1-3 rebirths to get back your lost Number. That's not a big deal UNLESS you barely reach your farming zone.

It's also worth noting that you'll likely be able to tell within the first hour (or even less) whether it's going to work out better, and you can change direction as needed.

[pac230]

You almost certainly want to switch up from Scissors: Scissors has no exponential element (on the main augment), so it doesn't scale very well.

Outside the occasional Challenge, you should never be running your Augs for all that long in any given rebirth. You certainly don't need to run them over night: that Energy should be going into NGUs.

I'd suggest running your Scissors combo for a fixed length of time (no more than 5 minutes), and then running the next Aug pair down for the same length of time. Then check the tooltips to see how much Stat Multiplier each one is giving you.

If Milk is stronger, then you can compare it with the next pair down in the same way, etc.

[Dragoslove]

The hard part about stating a level for cutoffs is that people get different amounts of cap/power/bars, and it's nearly impossible to balance that when describing what is best. I'm at 800-900K energy cap with 370K power (2800 base) and have found that for right now Energy Buster with Charge Shot seems to be the way to go. I've finished the laser sword challenges, but laser sword upgrades still take three minutes. Advanced Exoskeleton is getting close only taking 0.1 seconds base, but I think I still need some more power before it really shines.