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To be fair though, it doesn't matter all that much unless you level them quite a bit and do 30 minutes rebirths for a while (if you have the 30 minutes fruit activation for fruit of power beta and fruit of number the 30 minutes are not too bad for challenges so it's how I powered up my macguffin bonuses).
Blood macguffin can be good until you jump into evil difficulty, it becomes completely useless there for a while, the improved macguffin drops and improved macguffin itopod drops are both fairly decent ways to level your macguffins but itopod drops random ones so it can take quite a while to get decent levels through that (but you are still getting your PP so macguffins are just the icing in that case).
More info here: https://ngu-idle.fandom.com/wiki/MacGuffin_Fragments
For me, my priority would be:
1) Energy/Magic Cap (good for everything BUT also helps you getting Achievements faster -> more APs)
2) Energy/Magic NGU speed (since NGU gives plenty of useful bonuses)
3) Energy/Magic Power (good for everything BUT also helps you getting Achievements faster -> more APs)
4) Gold and Drop chance (Gold drop can help with No Time Machine challenge and drop chance for later zones may be like 1% so every bonus is good)
5) Bars and Beards are meh for me, but it depends on your build and amount of MacGuffin slots.
Also, keep in mind AFTER MacGuffin reaches level 100, each other level gives less bonus - it is better to get MacGuffin to level 100 ASAP (level it up with magic, Yggdrasil fruit etc.) and then level it up naturally through ITOPOD.
BUT there are 3 MacGuffins that give same bonus AFTER level 100 - Gold drop MacGuffin, Stat Macguffin and Augument speed Macguffin.
Also once you rebirth, MacGuffin bonus is saved and you dont need to have MacGuffin equipped to enjoy this bonus. So you can always change your strategy without losing your progress. Anyway, before reaching decent level of Macguffin i reccomend using that with highest level - no need to farm bonuses from level 1 NGU Macguffin while keeping your level 100 Bar Macguffin laying around (shouldnt happen anyway, but just saying)
Oh I meant the blood macguffin spell, not the macguffin that raises blood magic...
Anyway thanks...the only low lvl macguffin I am raising is the gold one...since it usually takes me around 4 hours to get one...I guess I should focus on easier ones for now.
There is no reason to bother with them until you have 10+ slots and they are all lvl 100+ (by then your bonuses will be around 5-10% which still hardly matters, even less until then).
I would say the first evil titan was the moment to start developing MacGuffin strategy. He drops a lot of them, there is another "+1 lvl to all drop" set bonus and I had MacGuffin beta yggdrasil which very quickly become main source of levels pretty much leaving all previous "efford" in dust.
Every moment you spend outside ITOPOD is much greater loss then what could possibly Guffins get you.
From the end of normal difficulty and onward itopod even becomes the best place for boosts as well, leaving only getting gold to kickstart the time machine and farming gear as the only reasons to not be in itopod.
Of course if you really want to start your macguffins you can still go farm them, it's not optimal at all but not everyone focuses purely on what's the most optimal.
I did go out of my way probably quite a bit more than most people to train the bonuses from my macguffins (with the 30 minutes rebirths) and even then I am only getting 1,100% to energy and magic power or 790% to adventure stats (and I am pretty close to what is currently the end of the game's content, having started the game close to when it initially released on kongregate).
So it's not like they are completely worthless but if you really want to get their bonus going it will take a while and you will have to go for 30 minutes rebirths that are far from optimal (too "long" for challenges and too short for normal rebirths).
I am on evil difficulty, i have 10 slots only, BUT MacGuffins are giving m, among other things, 160% energy cap, 150% Magic cap, little less power and NGU power but geez, that impact is huge. MacGuffins helped me greatly with achievements and later with APs from challenges.
ITOPOD gives little PPs on normal, but with NGU (you need MacGuffins for that!) you will get more later.
You need to understand this game is always tricky about one thing - you need to abandon something to achieve something.
Want to farm PPs? Well, you cant farm sets. Want farm sets? Well, no PPs for you during that.
Want more QPs? No PPs from ITOPOD. Want faster MacGuffin growth? Do 30 minutes rebirth that gives no Titans, no beards etc. Want to levelup beards? You need to do 12-24 hour runs.
Result of this? Everyones point of view is neither right or wrong and there is really few playstyles that can be considering "objectively bad" (wrong priorities in AP shop, spending XPs wrong way, not respecting efficient timers for features, ignoring certain features etc.).
If nothing else, farm Energy Cap MacGuffin - you need tons of energy for Advanced training and you always will (among other things, for ITOPOD) and E. Cap is the best for it.
If you still spend most of your time in normal zones trying to farm them, it might be that your drop chance is a bit low, makin the farm of gear and boosts take more time.
That's why I've started farming for Item Drops Macguffins...I can only bring my drop chance to around 2% in the badly drawn world...the beardverse wasn't a problem at all...but I felt like the badly drawn world was a giant leap in power and drop chance for me...my progress slowed down a lot after wallderp that's why I tought macguffins were the way to go since it is the most recent feature
If you ask me which MacGuffin i regret using my slot for, it would be Drop MacGuffin (and Beard and Bars, but i never used them).
This means that for drop chance you would have equipment (forest pendant and looty's lines in particular help a lot but ring of greed is also pretty good at that point), blood magic (blood spaghetti), NGU, gold diggers and beards as "major" bonuses.
And on top of that you have macguffins and the fruit of luck, both of those being a bit weak but even just a bit is better than nothing.
Also fairly important to note is that 2% when it takes you 20 seconds per kill is not the same thing as 2% when it takes 5 seconds per kill for example, so higher adventure stats will also help you get a lot more drops (this is also the reason why farming for drops is usually better done in an easier zone where you clear enemies in no time).
Can't afford 30mins runs now. The loss of daily XP/cap/power/drop chance/adventure would be tremendous due to loss of banks, PP and Yggdrasil. There goes my hopes Guffins might be worth it when I get 100+ levels but they're still not.
I will do some boosted 30mins runs when I hard reset for the first challenge set and quests (when they all fill up). But that's opportunistic. PP and Yggdrasil hit will be huge, probably not even worth it.
And that's context we are talking about. On normal difficulty it's not worth much spending hours/days/yggdrasil dedicated to Guffins for a few levels or some 1-10% bonus (even if you could get it as I don't see how with that few slots/and like level 30 at best Guffins). And at the early Evil it's still not worth farming because you gain many levels from other sources as well as bonuses from Guffins are still pale compared to the grow you get from 24h runs (which is currently +15-25% cap/power/bars per day).
So postponed Guffins even more and I guess they will be eventually worth more later (higher levels + XP cap/power diminishing + cheap PPs depleted). But when that happens I do not now.
Also not sure about achievements because even I already have all of them so there was nothing Guffins of the past could even do for me.
It's a similar debate to the whole "what's the best ratio for power, cap and bars" or "are super long rebirths really worth it", people come up with different answers depending on their own experiences and on what they find more important.
I know I grinded macguffins while doing normal challenges (both grinding their zones and doing 30-ish minutes rebirths), I also extended my grind in quest areas to grab a macguffin in each quest for quite a while and outside of the troll challenge I completed the evil challenges with 30 minutes rebirths again.
It definitely lowered my overall exp during those periods of time and I was getting less PP as well but I definitely didn't regret it, especially when I was grinding at the exile and noticed that my macguffins stats were quite high compared to other people and they were helping me quite a bit.
Would I have progressed faster all the way to where I am now without that?
Hard to tell, at least not by a large enough margin to make a real difference.
Would I have been slower without it?
A few things would probably have started running at full speed a bit later than they did in evil without those bonuses but again the difference would be days, maybe a couple weeks at most (it might seem like a lot but it really isn't when you are grinding at the exact same place for a few months and not seeing the next zone in the coming months without an update helping).