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You can throw the potion at her anytime during the encounter. You might even be able to hit her with it outside of the encounter or while she's shapeshifted and still have it work, but I haven't tried that.
The first time I did this fight right when the game released I did miss with the potion, but it still worked regardless. On this latest patch, I missed and it didn't work, so maybe they fixed that.
You still have another way to save Vanra if you miss with the potion, however. Just make sure to turn on the non-lethal passive for the group and make sure someone with a melee weapon attack gets the final blow.