Best big/main mods for the core of a super modded playthrough?

[Pyroblap]

Trying to decide on the big content-heavy mods for a multiplayer OP/Fun run playthrough but have limited experience with several of them.

They'll be sitting alongside other mods that vastly increase the player's power cap like Antisocial, Dual Wield, and Luiafk.

Can you pick your top 2 and tell me why?

Calamity
Thorium
Spirit
Elements Awoken
Ancients Awakened
Tremor

Please feel free to write in suggestions --big/'main mods' only, please

Thanks!

[Cryst]

vANILLA

[8gah]

calamity and thorium, i would say those are the best mods for all the bosses they include, thorium also includes a 2 new classes both of these mods have post ml stuff and the difficulty is just unreal in calamity

[Chernobyltoast]

extra item stats is fun and powerful

[Panda]

Brooo yeh i would

[Sofi]

i choose em all

[The Snopingasusual]

You should pick Mod of Redemption and Qwerty's random content mod too because there are some bosses with interesting patern and new "dungeons" structure.