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I got good results with the Molten Fury and Frostburn Arrows.
You'll also want a decent arena to block off those homing skulls.
Weapons-wise, anything you're comfortable with should do the trick. Last time I did it, I used a star cannon for his arms (took me around 200 stars I think) and finished off the head with a bee's knees (forgot to equip Queen Bee's accessory, so it could have been easier/faster).
Use a Minishark with Meteor Bullets. Once both arms are down, keep firing at his head with your Minishark, and when he spins, smack Beenades against his head. His homing skulls will be relatively easy to dodge when his arms aren't beating the crap out of you.
Craft some Spectre Boots, and if possible, get a horseshoe.