should i get end E for a first ending?

[kir gold]

its the most easiest ending that i can get right now, but should i? maybe better get a ending A for the first ending?

[Klampus]

Doesn't matter, the game doesn't record it or anything, and you can unlock the hidden mode even with ending E.

Did you get lucky with equipment drops, etc? If you are in good shape, try and get as far you can. If you just want to start another run / try another character, then just get ending E and use what you learned for the next time around

[kir gold]

my characters have all limbs, and i found nice blue plant spawn(with red what is nice) so i gonna get ending D too

[Klampus]

better yet, why not just play the game blind and not "go for" any specific ending? Especially if it's your first time

[CtenosaurOaxacana]

Ending E is the easiest, because it's the typical unresolved 'the end?' you earn when there's still at least a few entire areas untouched in-game. But whether you complete (or fail) the initial quest objective, then you can just attempt to leave the dungeons.

Ending C & D are the 'regular' ending paths, leading to some insight & lore about party members, an inescapable weird place with a powerful wandering monster that you play 'hide & seek' with, and 1 or 2 more bosses as well (potentially 3 on harder difficulties). I'm counting the last boss in Ma'habre too, because they're not necessary to fight for the other endings.

Ending A & B are the 'hard' ending paths, leading to a literal gauntlet of painful and sometimes lethal traps that would make the architects of Sen's Fortress blush, with lots of precision timing outside of battle. Shout-out to that one yellow lizard-mage positioned so that they will take an arm or leg off if you ♥♥♥♥ up your dash. Then at the end you face either one of the two hardest bosses in the game.

Character exclusive 'S' endings are technically the hardest, since you can only get them on the hardest difficulty solo mode. But they also have unique requirements to complete, so some routes are easier than others.

I'd rate their difficulty from easiest to hardest like this:
Cahara & D'arce <<< Enki <<<<< Ragnvaldr
or to put it another way:
Treasure hunt & Scroll hunt <<< NPC stuff + Ending D <<<<< Unique kill collector