Lottery Winner! & Mega-Brutal Shuffle

A guide for the following four achievements: 'Lottery Winner!', 'Mega-Brutal Shuffle', 'Bingo!' and 'Normal Shuffle'
SInce you will also get the normal difficulty achievement after achieving the Mega-Brutal difficulty version, I will only give directions on 'Lottery Winner!' and 'Mega-Brutal Shuffle'
It requires some understanding of beating the game on Mega-Brutal difficulty, which you can find on other guides.

Get a good start

Start as Bacteria
Evolution gene: Sympto-Status
Choose other genes according to your own preference

These achievements require winning 5 times in a row and it seems devastating due to randomness
However, as long as you don't lose in the game, you keep your win streak
So you can restart over and over until you get a good start (I mean 'good', not insane)

I will show you what are good starts for 'Lottery Winner!' and 'Mega-Brutal Shuffle'

Lottery Winner!

As long as you get transmissions and abilities, it is a good start.

Now just beat the game on mega-brutal with a head start.

Mega-Brutal Shuffle

This one is tricky and requires some luck
All evolutions are mixed up and you could only see few of them when you start the game
I strongly recommand to give it a shot when you see Extreme Bioaerosol in the beginning


Basically, Extreme Bioaerosol is stronger than Water 2 + Air 2


In the midgame, you need to find Drug Resistance 2 ASOP, try to evolve useful abilities while searching for it. And this is why I chose Bacteria ---- its special ability is Bacterial Resilience: all stats slightly increased.
This is how you may find Drug Resistance 2:

In the order of:
Drug Resistance 1
Environmental Hardening (really good!)
Bacterial Resilience 1
Bacterial Resilience 3
Cold Resistance 1
Drug Resistance 2


Good Luck!

Wait......Just a minute!

Instead of actually winning 5 games in a row, there's a better way!

Same as unlocking all the genes within a few minutes, just save the game right before you win.


You would get the achievement by loading 4 times in a row!
It is cheating indeed, but you have to admit that it's pretty damn good.

[CordisDia]

I will just confirm what @Aesyle said ...

[Jefe Sonirraft]

My game was reset when i was doing this achievement, help! :(

[Aesyle]

Update: So, picked only one cheat at a time and it works fine. Just got my Bingo! and Lottery Winner! achievements. And save load trick also works. (Btw, i'm using Nano-Virus to do it.)

[Aesyle]

When picking Suffle Strain and Luky Dip, both at the same time, in hopes to get 4 achievements at once (on Mega-Brutal), achievements doesn't count at all.

[『Emillian』]

Thank you very much. Also the save trick still works.

[AlexSargon]

Am I doing it wrong, or did they patch that out? Each time I reload my game right near the end (half a billion left), it wins and gives me the 1/5 message. So, I'm just starting my win streak over each time.

[InfraRogue]

That moment when you start with all three genetic reshuffles.

[NerdCuddles]

how do i do the random mode?
i want to know

[genesisfalls]

Not lucky, cause Organ Failure has too much lethality to START A GAME WITH!!!

[Microwaveee]

+An Arstotzkan Official omg so lucky