Simian Flu - Mega Brutal Guide (Guaranteed Win & Perfect Score)

This Plague was quite challenging and is very long so if you lose near the end you have to start all over and it can become quite tedious. But with numerous trials and errors (about a full days worth) I've come up with a guide that will guarantee you both a win as well as a perfect score as far as I know, no matter how long you take or % of cure, so long as you win you get a perfect score. I once finished at 1800+ Days with 94% cure and got a perfect score. With this guide you will of course finish much early with fewer scares.

(Note: On the unlikely chance that you do fail just remember to try the guide again and make sure you didn't miss anything like devolving dangerous Symptoms, All labs destroyed immediately, no step skipped, if really unlucky and a lab icon is hidden under your Ape Colony icon make sure this is the case and use 'Ape Rampage' on the Country or Countries in question, or you just make a fatal mistake. This guide will guarantee a win & perfect score if followed exactly and no user error.)

Simian Flu - Introduction

Simian Flu - Mega Brutal



It's very important that you follow this guide exactly and make no deviations and spend the DNA
immediately as it will soon be wasted on ridiculous genetic shifts, an unnatural ability to mutate symptoms we MUST devolve, and an onslaught of Labs and Drones that can easily lead to a loss if this guide is ignored. I'm not saying it can't be done another way and with better results only that this guide guarantees a win while my experiences with other methods while having scored better were unlikely to win all that often. STICK TO THE SCRIPT! :D

Here is a list of the Symptoms we must devolve ASAP if they are to mutate (also avoid evolving them till much later) as they will kill off hosts and speed up progress and if left unchecked will guarantee a loss if the infection isn't already unstoppable there at the end.

• Coma
  
• Dysentery
  
• Gastric Ulceration
  
• Hemorrhagic Shock
  
• Hydrocephalus
  
• Internal Hemorrhaging
  
• Meningitis
  
• Neuro-Enhancement 1
  
• Pulmonary Hemorrhage

Shall we begin?

Simian Flu - Genetic Code

The following genes are unique to the Simian Flu plague and you must unlock 2 of them which I recommend playing on Casual, saving just before the end, completing and unlocking a gene then loading the game again, completing to unlock another gene rather than starting over, rinse & repeat but know that this is still frowned upon and practice doesn't hurt.



Genetic Code-----

• Metabolic Jump
  
  • With the amount of reds will be popping throughout the game especially after we evolve the 'Hominidae Bridge' this will come in very handy with increasing how much DNA we obtain.
• Ion Surge
  
  • (Requires Simian Flu Gene Unlock) This Gene is quite important with the number of mutations especially highly lethal symptoms that we'll need to devolve.
• Aquacyte
  
  We would very much like to infect Island Countries as well as those across the Atlantic! To avoid headaches later and this helps.
• Extremophile
  
  • We need whatever edge we can get and a bonus to all environments allowing us to spread the infection world wide is an edge even if slightly dulled.
• Together Strong
  
  • (Requires Simian Flu Gene Unlock) As we will be relying on Ape Colonies to win this, having a bonus for these is a no brainer.

Simian Flu - Choose Starting Country

As much as I would have liked to use my favorites like (in order of preference) Saudi Arabia, India, China, South Africa, or the UK, I found these unreliable and for good reason. We'll be using abilities to destroy labs (extremely important to do so fast and keep cure progress down/fall behind), move our colonies when drones attack, or travel to a lab that doesn't have enough infected monkeys to attack it which can cost you the game. This is why I chose Central Africa for it's proximity to all Countries but also allowing us the ability to deal with North, Central, South America, and Island Countries.

Simian Flu - Abilities :: Phase One

• Simian Neuro-Genesis
  
  • We'll be needing this ability to increase ape intelligence allowing for Ape Colonies and beginning what will be the age of the apes! "Planet of the Apes" and all that...
• Ape Colonies
  
  • These colonies generate DNA and are vital to our success as genetic shifts can devastate costs rapidly.
• Immediately place a Colony in our starting location of Central Africa.
  
  • One thing to keep in mind is that the Colony Icon overlays all other icons with the exception of the drone so if a Lab is completely missing having heard it being built it's possible it's under one of your Colony icons so place them well. In this case we've already destroyed the initial lab so place it center to avoid blocking land mass in other Countries.

Now to finish up phase one abilities!

• Cognitive Shift
  
• Educatioin
  
  • These two abilities boost the amount of DNA we receive and gives the game time to unlock Countries bordering our Colony to open for more Ape Colonies as sometimes you won't be able to place a colony and have to wait it out (Usually but not always noticed when you see a green highlight over a Country without you mousing over it).

Remember to Devolve the symptoms listed in this guides Overview ASAP if they mutate.



Open Symptoms and Devolve

Simian Flu - Transmission :: Phase One

• Inter-genus Dissemination 1
  
• Sebaceous Excretion
  
• Blood Gift
  
  • As mentioned under Abilities it's possible that Countries are not yet ready for Ape Colonies so we should help spread the infection with the above transmissions which will help now and later on.

Before we start evolving more abilities we want to setup some Ape Colonies a.k.a our DNA Farm. This requires patience, grabbing DNA as soon as it's available, devolving any nasty symptoms if any mutate during and remember to keep doing so until our infection can't be stopped and we want death!



Once you see the ability (Z) to create an Ape Colony press it and select a bordering Country (preferably a large one trying to avoid hiding future Labs that must be destroyed before they start boosting the cure. Make sure to create 4 new colonies totallly 5 altogether with the initial one we created at the start.

Simian Flu - Abilities :: Phase Two

• Primal Awareness
  
• War Paint
  
• Covert Expertise
  
  • The following abilities help Apes hide/blend in to avoid detection as well as improved combat skills taking down labs faster.
• Organized Travel
  
• Logistics
  
• Seafaring
  
  • To avoid Drones as well Infect Continents and/or Islands that are being stubborn we'll very much want this ability
• Ape Rampage
  
  • Labs are by far our biggest danger and so with Ape Rampage and War Paint we now have our last and most important ability. Use it whenever you catch a lab in the stages of creation! If for any reason it's grayed out immediately use 'Organized Travel' from the closest land mass possible (not grayed out) and send them to the Country with the lab. Once reached immediately use Ape Rampage to destroy it (be quick).

If we were unlucky and the Continents on the east side of the Atlantic (N,C,S America) show no infection (Open world map to see) then be sure to use 'Organized Travel' on a Country that DOES NOT have a colony (this would waste the Colony's time and DNA generation and it's nice to have them bunched up for convenience sake when clicking bubbles) and send infected apes over to South America so we don't get caught with our pants down when it's time to crush labs out of reach.We'll get to Islands soon! If we're lucky Genetic shifts have not done too much damage but expect to hit 100+ DNA for final Ability.

• Cold Resistance 1
  
• Drug Resistance 1
  
• Genetic Hardening 1
  
• Cold Resistance 2
  
• Drug Resistance 2
  
• Genetic Hardening 2

Simian Flu - Transmission :: Phase Two

Be sure to set speed to 1 just before evolving the final transmission for phase two 'Hominidae Bridge'

• Inter-genus Dissemination 2
  
• Cutaneous Transfer
  
• Submissive Conception
  
• Excrement
  
  • Further infecting the ape community with our infected apes.
• Hominidae Bridge
  
  • Be sure to set game speed to slowest (1) as we should be pretty overwhelmed (depending on genetic shifts and the infection spread already) that even pro clickers will miss DNA. This transmission allows the infection to jump from ape to human and so a lot of red bubbles (glad we inserted the 'Metabolic Jump' gene)!

Simian Flu - Interlude

We should be alright but want to guarantee we have the DNA needed to see this through so save up and let's place our 6th and final Ape Colony for our DNA Farm.

It's probably a good idea at this point to check the world map and make sure all Islands are infected. If not do not wait on boats but use 'Organized Travel' ability to them all (again DO NOT select a Country with a colony present).



If it hasn't already, SOMETIMES the game will announce a lab is working on a cure and it's location. This is Gen-Sys, so use your peripheral vision if you don't see or hear it. We must use the 'Ape Rampage' to destroy it immediately. Sometimes all we'll get is the sound of construction with an Icon that is hopefully not hidden by a Colony but with bubble popping, music, and other distractions this might be missed so, sometimes just the icon (again if not hidden by Colony icon, thank you a.devigili for this but if you can't find the lab you heard created you can select a Country and check if you think another icon is hiding it) with no sound which I believe is a bug so keep your eyes open and using 'Ape Rampage' destroy each and every lab that pops up, if you see a blue plane not spinning but flying towards a destination it will eventually land and create a lab. This is our priority over everything and if one is left to research your cure progress will skyrocket and you will lose.



We also have Drone's to worry about. They'll eventually pop up and usually target one of your Colonies so we'll need to use 'Organized Travel' and move our Colony to a bordering Country (don't want to waste time sending further away) but make sure all Colonies are out of the Red blast zone which turns blue when safe. Quite often they'll attack random Countries leaving your Colonies alone so you need not worry about them at this time.

Simian Flu - Transmission :: Phase Three

• Air 1
  
• Water 1
  
• Air 2
  
• Water 2
  
• Extreme Bioaerosol
  
  • We need to infect the world faster! If you find poor nations taking their sweet time and can afford the DNA go ahead and evolve Blood 1 and/or 2 but this should not be necessary.

Simian Flu - Symptoms

Be sure to check that all Countries are infected and that the most recent (be sure to check Islands as well) are speeding along infecting their people. If still slowlying picking up momentum wait until it's clearly unstoppable. At this point we can let whatever Symptoms mutate without concern!

Eventually the infection will take over and



Time to use what DNA we have to wipe them out with the most lethal of Symptoms. Here are an important few to speed things along in order of HIGHEST lethality.

• Coma (Didn't expect this to be so dangerous huh?)
  
• Meningitis
  
• Pulmonary Haemorrhage
  
  • Feel free to spend DNA as you like from this point. I recommend checking for the more lethal symptoms to end their misery quicker.

Simian Flu - Conclusion

I would very much like to see the Lab Icons either overlay the Colony Icons or highlight a Country because missing just 1 can be quite devastating at the very least towards your confidence in winning. I'd recommend disabling music for this one but again sometimes there is no sound of a Lab being built.

Still if you followed this guide and kept a watchful eye you should be quite ecstatic as you've just achieved your Simian Flu-



This scoreboard is from my final test before I was sure it was a guaranteed winner!



I hope this guide was easy to follow but if you have any questions, issues, etc with this Guide or any of my others which can be found under my discussion Guides for Mega Brutal & Perfect Scores please let me know and I'll get back to as quickly as I can!

For those that don't follow my Weekly Contagion & Other Indies Stream & Giveaway I did one for Plague Inc: Evolved if you'd like to check it out!

Sorry but it does not let us embed a time-stamp. Plague Inc: Evolved portion starts at 5mins 10seconds.

I'll be away a bit at the hospital for an infection (haha that's what I get for all these guides! But don't worry) and when I get back I hope to start on the Scenarios! Thank you all for your support and kind words on the previous 9 guides and can only hope to see the same on this final Plague 'Simian Flu'.

[kiruhacorni]

Second try, thanks! After that, I have all diseases on mega-brutal and you help me with that a lot!

[deadface]

It's hard and you may have to experiment a little but, but works

[Terrorism Gaming]

Dude thank you so much for this tutorial

[ΞΩ|PROVIDENCE|ΩΞ]

Impossible when you've got mutations happening every five fckn seconds.

[harley<3truejon]

OKAY UPDATE I DID IT :D THANK YOU SO MUCH

[harley<3truejon]

I just won but didn't get the achievement gonna cry

[Fumo Bnnuy n Frends]

huh

i did not know you could unlock genes by save loading and on casual

thanks for the tip imma do it to unlock all genes for all diseases

[Nyxia]

Thank you so much

[Nyxia]

First try, wiped out humans in 1852 days

[blueyandicy]

I literally did this first try with some save scumming (you would not BELIEVE how many times the stupid mf awareness day came up.) 10/10 guide, tysm dawg