12 GB in dual channel mode?????

[FLHWYPATROL]

Could I put two ddr3 4 GB sticks at 1600 Mhz (in the right slots of course) along with two ddr3 2 GB sticks at 1600 Mhz without reducing my entire memory bank to lower channel performance or bandwith?

People have been saying that you need one or two pairs of matching sticks for dual channel mode to work. Does that also include that you need the same amount of ram per memory module?

[UberFiend]

2 sticks in each pair need to be the same spec (timings), but the pairs can be different sizes.

If the 2 pairs are different specs the whole setup will operate at the rate of the slowest pair.

Put the larger pair into slots 1 & 3 as they are first in line & the smaller pair in slots 2 & 4.