Loading screen takes long

[Perk456]

when I start up the gaming

[Cunin]

That's normal. It depends on your CPU/RAM setup, but it always takes long because it preloads/compiles stuff for later.

[Rasta]

men_bUseMenuSimulation=0
men_bShowIntroCutscene=0

and deleting Sam3All.log from \Steam\steamapps\common\Serious Sam 3\Log may help a little bit

[AlenL]

If it is very long (e.g. 10 minutes), it could be caused by old BIOS on Buldozer (some AMD FX) |CPUs. Please post Sam3.log so we can know more.