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Welcome to the co-op walkthrough guide for Resident Evil 5 on Professional mode. This is a Fresh Pro run where two players begin with the default inventory/store and just with the basic handguns. RE5 doesn't have New Game for Professional mode like RE4 so you must make a fresh start by yourself. You will need to create a new save file and join or being invited to a Professional online mode. Then start with someone at the beginning of the game and play until first checkpoint. After that you will unlock professional difficulty. On this hardest difficulty, enemies are much more tougher and violent. To make this even more challenging me and my partner didn't use any upgrades through whole campaign. This walkthrough is strategy guide aimed at helping players learn how to deal with each chapter without taking damage and to get S-rank in all chapters.
Note: I don't know what Capcom was smoking when they came up with smg like this but Chapter 2-3 is total BS. There is scripted damage when last truck hits Chris and Sheva's Hummer. Technically, your vehicle is damaged (not characters), but still... That's why my partner and me didn't put No Damage accomplishment in the title.