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Those choices caught me off guard a bit there. I thought I was the only one who liked Plutonium Hunger as a singular stand alone mutation. However I am currently not so convinced by Sharp Teeth; waiting on a run to prove me wrong in time.
For example, If offered plutonium hunger early in the game, I always grab it. I have low impulse control and a prepensity for greed, so it saves me from rushing into dangerous areas to grab rads, which is the cause of my death probably 80% of the time.
Effectiveness also varies with how these are combined. Eagle Eyes+Recycle Gland+Minigun is pretty brutal, as is Bolt Marrow+Auto crossbow.
I haven't found Sharp Teeth to be worthwhile at all yet. I find I get the most benefit from Racing Mind with melee weapons.
That is a good point... will add them to the original post.
1. Boiling Veins
2. Scarier Face
3. Rabbit Paw
4. Rhino Skin
5. Second Stomach
6. Laser Brain
7. Impact Wrists
8. Throne Butt
9. Back Muscle
10. Blood Lust
11. Euphoria
12. Racing Mind
13. Stress
14. Recycle Gland
15. Long Arms
16. Shotgun Fingers
17. Bolt Marrow
18. Plutonium Hunger
19. Extra Feet
20. Lucky Shot
21. Sharp Teeth
22. Eagle Eyes
23. Gamma Guts
24. Last Wish
Laser Brain goes way down if you're not using those weapons, but for a general run you're probably aiming to pick up at least one so that's why I have it so high--it also fits at spot 13 to go with the group 14-17. Mutations 14-17 really depend on whether or not you're even using those weapons, but I think they're each about that effective for those respective weapon types, depending on exactly which weapons you're using. A few of them can easily be interchanged and some of them can be changed by a lot if they fit your playstyle (I personally really like Back Muscle but it might not be as useful for everyone), but it seems about right to me (the original list is pretty good overall, I have to say--mine isn't radically different). Some of them are also character dependent.
The ones that are hardest to place are Stress (I don't personally like it but it seems about as good as racing mind...it's particularly good with Chicken and Boiling Veins), Extra Feet (could easily be much higher if it helps you about as much as Euphoria), and Lucky Shot (seems like getting free mini-presents because you often don't get the ammo you need--it was recently changed, though, and I'm not sure how much it helps you in the end game, so it could be good). Eagle Eyes could also go higher if you're using weapons that really benefit from it.
Then again, I have not yet looped even once so...
Top Tier
Boiling Veins
Rhino Skin
Scarier Face
Blood Lust
Rabbit Paw
Impact Wrists
Upper Tier
Plutonium Hunger (I think PT is highly underrated)
Back Muscle
Euphoria
Second Stomach
Lucky Shot
Racing Mind
EDIT: Laser Brain (The energy based weapons are incredibly powerful and you'll want one when looping so LB rises above the other weapons specific mutations)
Mid Tier (Situational Mutations)
Throne Butt (Varies greatly between characters and what stage of the game you're at)
Shotgun Fingers
Bolt Marrow
Eagle Eyes
Stress
Long Arms
Recycle Gland
Low Tier
Gamma Guts
Sharp teeth (Love it with Rebel)
Last Wish
Extra Feet
It's hard to make a ranking without including synergies as the lesser picked mutations can really make for a solidrun
Eagle Eyes + Recycle Gland
Plutonium Hunger + Impact Wrists
Long Arms + Euphoria
Back Muscle + Lucky Shot (You'll always have ammo to use any weapon you find)
Sharp Teeth + Scarier Face (Almost anything with scarier face works well)
Extra Feet + Long Arms (Most fun you've ever had with the Shovel).
Then you have to add in the characters and it can all get really messy. I will say that Lucky Shot, Eagle Eyes, and Racing Mind are three mutations that I've gained a lot of respect for lately while Impact Wrists, Second Stomach, and Euphoria are three I don't value as highly as I used to.
- Boiling veins (the top pick every time I am being serious)
- Scarier Face
- Plutonium Hunger (good synergy with other mutations and Rush Crown)
- Rabbit Paw
- Second Stomach
- Blood Lust
- Rhino Skin
- Laser Brain (often gets treated as a weapon specific Scarier Face)
- Racing Mind
- Impact Wrists (gains a lot more value when combined with other damage mutations)
- Back Muscle (greater value when not using bullet/melee weapons)
- Throne Butt (high pick for Robot, Roids, Y.V. and low for Crystal, Chicken)
- Lucky Shot
- Stress (much higher for Chicken, Rebel)
- Eagle Eyes (gets a lot higher with Roids or certain weapons like auto-crossbow)
- Long arms
- Recycle Gland
- Extra Feet
- Euphoria
- Sharp Teeth
- Gamma Guts (often seems like a weak version of Sharp Teeth)
- Bolt Marrow (goes to the top if an auto-crossbow drops)
- Shotgun Fingers (would not take even if auto-shotgun and gatling slugger were in my hands)
- Last Wish (no no no)
Mutations that have moved up reciently; Boiling Veins, Scarier Face, Racing Mind, Impact Wrists, Laser BrainMutations that have moved down reciently; Rhino Skin, Bolt Marrow, Back Muscle
I would hold that plutonium hunger also depends on the character; I normally take Crystal, but if I was playing Chicken Plutonium Hunger would be dead last (want to save those health drops until I reeeeally need them).