Perform your first Takedown. Civilians don't count, so be nice.
Perform your first Hack successfully.
Up the Ante!
Upgrade your first weapon of choice.
Deal with Mr. Carella's indiscretion.
Fully upgrade your first augmentation of choice.
Put a grieving mother's doubts to rest.
Successfully hack at least 50 devices within the same playthrough.
Help a lady in the oldest of professions clean house.
It may take some sleuthing, but justice must be served.
Smash the State
Help Officer Nicholas take out the trash.
Help the Hive Bartender settle a tab.
Complete Deus Ex: Human Revolution.
Protect a client's interests by performing a less-than-hostile takeover.
The Final Countdown
Perform 50 takedowns within the same playthrough. (Civilians don't count.)
Cloak & Daggers
Deal with the man in the shadows.
Consciousness is Over-rated
Knock out at least 100 enemies in a single playthrough.
Follow Pritchard's lead to uncover the truth.
Deus Ex Machina
Experience all the different endings that Deus Ex: Human Revolution has to offer.
Descend into the bowels of an urban jungle and confront a warrior-priest.
Fully upgrade one of your weapons.
Complete Deus Ex: Human Revolution at its hardest setting.
Foxiest of the Hounds
Complete Deus Ex: Human Revolution without setting off any alarms.
Complete Deus Ex: Human Revolution without anyone dying by your hand. (Boss fights do not count.)
Read all 29 unique XP books within a single playthrough.