I'm currently trying out the Steam Linux beta and I've noticed a few problems with Frozen Synapse that I didn't have on Windows.
Firstly, CTDs. Crashing to Desktop is, I think, related to YouTube uploading but I'm not entirely sure.
There's also an issue with YouTube credentials not being saved, even with the box ticked. This means I have to alt-tab out and create a new program-specific two-step verification key each time I want to upload something.
And seeds are not being saved for missions completed, which means I cannot share the seed for the level after uploading a single player mission video.
I'm also having trouble logging in to the master server when the game starts up, though that only started recently and could be a network error.