I recently acquired a desktop computer with somewhat poor specs, so I threw Steam and SHODN on it to see how well it would run. I had Steam Cloud syncing disabled, so I was greeted with a fresh save. Figuring "what the hell, let's see what I can do", I went ahead and started a Ninja Roof run with the following:
Sadly I died on the final cycle of Abarghus, with him on two health. I entered OAN with a single life, and right before I died I was about a hundred points away from 300k and a life up.
Oh well :(
I managed to unlock the following in that single run:
Weapons: Nunchuks, Nunchuks+, Whip, Boomerang, Axe, Hadouken, Ricochet, Sticky, Wind
Upgrades: Time Lv. 2, Range Up Lv. 2, Bomb Up Lv. 2, Magic Up Lv. 3
Other: Rabbit's Foot, Magnet, Crystal Ball, Randomiser, Spike Away, Time Extension, Rage, Flashbomb, Monkey Bane, Soundtrack
All in all, pretty successful