The Binding of Isaac

The Binding of Isaac

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Paprika Jan 20, 2013 @ 4:53pm
What's the worst enemy in the game?
No, I don't mean bosses. More along the lines of things you'd see in regular rooms. For me, it would have to be those damn heart/mask combo guys. So many ruined runs caused by them.
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Showing 1-15 of 166 comments
Ya Boy, Paradox Jan 20, 2013 @ 5:13pm 
Yeah, i'll go with mask+hearts. They are specially annoying on Utero.

That and leeches. they always ruin me when i'm about to destroy mom's heart.
butch Jan 20, 2013 @ 6:44pm 
I HATE those rolling brains in The Womb. I can never beat a room with them without taking a hit... :|
TwerknlikeMiley Jan 20, 2013 @ 6:45pm 
yeah i totally hate those guys
i also hate those guys where you are suppose to attack their sides/back

i SUPER DUPER hate when you get a map with a thin walking area +2 greed heads+2 bugs
both shoot split shots -___-
Trace500 Jan 20, 2013 @ 7:16pm 
I don't have Wrath of the Lamb, but the worst enemies for me are definitely those Mr. Maws.
Dabeavis Jan 20, 2013 @ 7:21pm 
Leeches and certain spiders, but I am a bit of a novice when it comes to this game.
Cryten Jan 20, 2013 @ 8:52pm 
Plain spiders and the hearts + stone faces. spiders early will charge you before you can kill them and stone faces can box you in to a limitied movement room for multiple hits.
lost diaper Jan 20, 2013 @ 9:33pm 
*gets brimstome*

aww yiss!

*room full of spiders*

cenho09 Jan 21, 2013 @ 6:53am 
Greed Heads, no matter when or where, they always suck.
Oscypex [zhgswag] Jan 21, 2013 @ 7:00am 
Obviously Knights, the well-armored guys with their brains visible.
The Most assholiest of Enemies I can find are the selfless knights. They've proven to me that without Brimstone or Technology, I'm ♥♥♥♥ed.

Not to brag or anything, but the Mask + Hearts are somewhat easy for me. Iunno why. They just are.
Last edited by oғғιcιal oғғy; Jan 21, 2013 @ 9:08am
ユキ✭ツキ Jan 21, 2013 @ 11:12am 
Personally, i cant stand Chubbers, the things that shoot Lil chub projectiles at you, when i get lots of them in a run, they tend to wreck me
BoopyPenguin Jan 21, 2013 @ 2:55pm 
anything that shoots in multiple directions and jumps around. The fat flies and those bloody headless jumpers...

but the greed heads are the worst of all, i can never get out of a room unharmed with those lil ♥♥♥♥♥
I can handle the enemies most of the time. It's the room layouts that get me. Doing an Iron Man run? Got a map and compass so you know where to go? ♥♥♥♥ YOU TINY PLATFORMS WITH NO WAY OUT HAHAHAHAHAHAHAHA

So basically, any of those ♥♥♥♥♥♥♥s that rush you with no chance of escape, in tight room areas.
Beauty and Stupid Jan 21, 2013 @ 3:40pm 
The god damn weird...worm...♥♥♥♥♥♥ things with suits on. a room full of them = dead.
Maha.j2 Jan 21, 2013 @ 11:32pm 
Chubby Gluttony's. Why can their ♥♥♥♥in CHubby go through walls and mine can't!?
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Date Posted: Jan 20, 2013 @ 4:53pm
Posts: 166