Tiger7 Mar 30, 2013 @ 2:39am
Your Most Powerful Run
Mine was:
The Mark. Polyphemus. Mutant Spider. Growth Hormones. Odd Mushroom (Big). Coat Hanger
Little Gish. Little Chad. Skeleton Key. The Belt.
Cain.
Showing 1-11 of 11 comments
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Blingie Mar 30, 2013 @ 3:48am 
Oh i just had mine, if i remember correctly i had

- All speed 100%
- My Isaac was green and shot explosives, I thin its called Mutant Spider
- Deck of Cards
- Ankh

made rooms a breeze, to bad i died in the depths. x3
Sexy Iron Maiden Mar 30, 2013 @ 4:07am 
Technology 2 and Polyphemus. Arguably the best combo in the game attacking wise. If you combine this with flying and being ability to shoot through obstacles its ridiculous.

Took down mum in 10 seconds, took down isaac in about 15 secs. each room lasted about 4/5 seconds as all I had to do was go to a corner and 'sweep' the room.
Tiger7 Mar 30, 2013 @ 7:45am 
Originally posted by Blingie:
Oh i just had mine, if i remember correctly i had

- All speed 100%
- My Isaac was green and shot explosives, I thin its called Mutant Spider
- Deck of Cards
- Ankh

made rooms a breeze, to bad i died in the depths. x3
Its not Mutant Spider Its Ipecac
LikeABoss Mar 30, 2013 @ 4:33pm 
Sacred Heart, Polyphemus, Mutant Spider and Tammy's Head. I got about 5 health up pills so I could buy great devil room items like the Nail too. I loved it <3
DeViLMaN666_Qc Mar 30, 2013 @ 7:54pm 
Powerfull in term of damage with laser i would say this i was doing like x3 max damage + laser that deal multiple damage over time i was 1 shoting boss 0.o
http://steamcommunity.com/sharedfiles/filedetails/?id=131521556
Last edited by DeViLMaN666_Qc; Mar 30, 2013 @ 7:55pm
Blingie Mar 30, 2013 @ 10:09pm 
Originally posted by Tiger7:
Originally posted by Blingie:
Oh i just had mine, if i remember correctly i had

- All speed 100%
- My Isaac was green and shot explosives, I thin its called Mutant Spider
- Deck of Cards
- Ankh

made rooms a breeze, to bad i died in the depths. x3
Its not Mutant Spider Its Ipecac

Thats it!! thanks
Ninbi Mar 31, 2013 @ 4:17am 
Recently got Mom's Knife and Polyphemus. One shot all of Satan's forms, three shot It Lives and cleared out sheol easily.
ApplesAreBadForYou Mar 31, 2013 @ 6:47am 
epic fetus unicorn horn and full life with lots of soul hearts
Jawio Mar 31, 2013 @ 2:04pm 
nearly every item (not wotl) only about 15-20 i didnt get
Pieman Apr 1, 2013 @ 5:46pm 
My best run was absolutely insane. The character I used was Judas.

Book of Belial + Mom's Knife + Small Rock + Polyphemus + The Pact + Spirit of the Night + Ankh.

To put it into perspective, I only needed 6 or so shots to kill Blue Baby with this... and I was only on about 5 red hearts at the time.
PillowFort Apr 1, 2013 @ 5:56pm 
cain+brimstone+tech2 you have an always on brimstone that doeasn't need to charge.
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Date Posted: Mar 30, 2013 @ 2:39am
Posts: 11