~Adrian~ Jun 20, 2014 @ 10:58am
Best Run You Ever Had ?
What was the best run you've had and what items made it the best ?
Showing 1-15 of 61 comments
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Cabbage Cake Jun 20, 2014 @ 12:40pm 
Hmm.. If I had to pick one, I'd say it was the run where I picked up the pre-nerf brimstone and chocolate milk. Crazy rate of fire in combination with the raw damage of oldschool brimstone? Oh yes. Oh yes indeed. It's a real shame that the cathedral and chest didn't exist back then.
eew30 Jun 20, 2014 @ 2:54pm 
Cal Jun 20, 2014 @ 3:14pm 
The Rock, Sacred Heart, Spirit of the Night. I also had full stats for everything and 9 hearts.
DJ Chub N' Tuck Jun 20, 2014 @ 5:23pm 
Sacred Heart, Brimstone, The Mark, Lump of Coal, Holy Grail, and Thin Odd Mushroom (I want to say the Pact as well, but I can't remember). Got me the Dark Boy achievement easy.
ArgonArbiter Jun 20, 2014 @ 5:47pm 
Eve run with Ghost Baby, Little Chubby, Little Gish, Lvl 2 Meatboy, Little CHAD, Bum Friend, and Monster Manuel. Familiars everywhere!
(Didn't win though)
Jacio Jun 20, 2014 @ 6:28pm 
While I don't think it was my best run, having a Habit+Scapular+D6 was probably my favorite combo that I've ever gotten. Got pretty far and I was able to reroll Treasure Rooms as much as I wanted until I got something good.
bluephoenix150 Jun 20, 2014 @ 6:31pm 
Puppy suits is good enough.
Muju Jun 20, 2014 @ 7:53pm 
candle, full mapping, brimstone, mutant spider, money=power (with 99 coins), and some various tears up. that was my first isaac kill too.
stupendous man (Banned) Jun 20, 2014 @ 8:14pm 
I love me some Judas. I love damage.

Poly on B1, Rock also on B1, Pentagram as a drop. On B2 i got the teeth shooter majigger, and a Slow down - Spider in the Secret room. C1, uninteresting "infestation". C2, dog head (dmg), and a superfast shooter mushroom. I didn't get anything good in the Depths, but with my damage + book of belial, I 10 hit Mom, and her heart.
The Media Sponge Jun 20, 2014 @ 10:47pm 
I once managed to max out every stat but range, but I also had a super-charged Brimstone so it didn't matter in the end.

TartanLlama Jun 21, 2014 @ 3:57am 
Brimstone with Sacred Heart, the Candle and Polyphemus. Pretty much one-hit everything.
Agan Jun 25, 2014 @ 1:49pm 
Dr Fetus with Bobby-Bomb and Mr Mega. Basically giant homing bombs of instadeath.
Amaterasu Jun 29, 2014 @ 9:06pm 
when i had guppy with epic fetus with x ray vision
Notmrp00tis Jun 29, 2014 @ 11:58pm 
I had 4 Heart containers as Cain, I also had the Parasite, The Pentagram, The Small Rock, Book of Belial AND I became Guppy. Pretty damn good, If I do say so myself.
Rotation Point Jun 30, 2014 @ 12:35am 
Polyphemus + Brimstone = Rest is history...
Last edited by Rotation Point; Jun 30, 2014 @ 12:36am
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Date Posted: Jun 20, 2014 @ 10:58am
Posts: 61