Why so much ignorance and hatred towards this program?
Personally I prefer this interface and workflow to that of Blender... I am a Maya user and I own Maya 2012, I also own and use Zbrush.
I suppose if you're only learning and want the student version of such applications to be hired into a big company that will provide such high cost softwares then it would be fine for some of those comments of "just get 3ds max or maya student version" and for those of you indie developers and hobbyists applications like this are going to be a blessing in disguise.
Not only is this cheaper than the $3,500 price tage on Maya or 3DS Max, but if you do get those softwares under the student version you're not able to use them commercially and those of you who do not care then I feel sorry for you... For those only looking to create personal mods forgames and such I guess that would be fine to do as well.
If you're on a tight budget but want professional software then things like Silo would be ideal but before many of you start screaming and throwing your rattles out your pram... Here is something that I want to say! - There are some GREAT free alternatives, such as Wings3D and Blender, but that being said, some people just can't get on with blender very well and I personally believe that Silo2 is more intuitive within its workflow and interface. It's easier to grasp and doesn't boggle you down with a million features, however Blender would be an ideal application for those who are wanting to get intot he industry without spending any money, but like I have said if you cannot get on with it very well someting like Silo for just creating models and uv maps for your mesh's then I would suggest you try the Demo of SIlo2 as it is more efficient, but don't pay attention to those hating because this cannot rig or animate your models as it's not intended to anyhow. Along with Blender there is the aforementioned Wings3D which I started out with way back before I started learning maya officially. The reason for that was I began freelancing to make money to pay my way through training and such. Well that was a great application and it's getting even beeter but much like Silo it soley concentrates on teh modeling and uving aspect of model creation... It's great for what it is, and it's free but it's not as good as Silo2.
Now that I have that out of the way, nobody can say that I'm being "stubborn" as someone here on the forums put it.
If you are not in the industry but would like to begin learning to create game or production ready models and have the ability to freelance and make money off of your work (outside of Blender) this is probably your best bet, providing you can grasp the interface and really easy workflow! - Don't listen to other people, including myself... Try them all before making a solid decision and you will likely see where I am coming from with some of the software(s) mentioned here.
The sculpting tools are good but they have nothing on Zbrush, but at the same time Blender has sculpting tools but they also suck compared to Zbrush and the're still in development. Although you can always create your base mesh within something like Silo, Wings3D or Blender and then use a software such as Sculptris for the sculpting, but be ready to have some serious patience if you're trying to sculpt hard surface materials
Let me lay this out like this,,, In most cases there will be multiple people working on things, one would create the mesh, one would texture it, one would rig and or animate the mesh. Sometimes us indie developers do not have this luxury and find ourselves having to take up more than one of those jobs, often enough we will use multiple softwares within our workflows. I believe that Silo2 is a healthy addition to anyone's workflow.
If you do not plan on going to university for this type of thing and want to make it your carreer here is the least cost effective route for creating your models and having them look amazing without spending your entire savings. (of course excluding the free alternatives which are perfectly viable options)
Silo2 > 3D Coat > (Whichever image editor you prefer, for painting textures)
now you could just as easily use something like Sculptris for what you would use 3D Coat for but it's VERY limited and 3D Coat is the cheapest alternative to creating really nice character sculpts and efficient topology outside of getting ZBrush.
I hope that this has helped a few people explore for themselves and make a healthy and open minded decision based on their needs and this is not simply me trying to help sell this application but make everyone aware of the possible free options whilst attempting to explain why this is worth buying. I think it's a great start to the 3d modeling side of the industry. Try it for yourself and go over the official tutorials on the website, they will show you how easy the application is to use!